排序方式: 共有28条查询结果,搜索用时 218 毫秒
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目的:观察黄连解毒汤治疗肥胖型2型糖尿病(type 2 diabetes mellitus,T2DM)的临床疗效。方法:158例肥胖型T2DM患者随机平均分为观察组与对照组,观察组给予黄连解毒汤治疗,对照组给予二甲双胍治疗。比较两组患者血糖、减肥效果、糖化血红蛋白、体质量指数等。结果:两组患者在降糖、减肥方面的有效率比较,差异均无统计学意义(P>0.05)。治疗后两组患者空腹血糖、餐后2小时血糖、糖化血红蛋白、体质量指数均显著降低(P<0.01);但治疗后两组之间比较,差异无统计学意义(P>0.05)。结论:黄连解毒汤治疗肥胖型T2DM疗效显著,不良反应少。 相似文献
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目的:建立清胃黄连片的质量控制标准。方法:采用薄层色谱法对清胃黄连片中黄芩、黄连、黄柏、甘草、知母、桅子、赤芍进行定性鉴别,采用高效液相色谱法对清胃黄连片中的黄芩苷进行含量测定。结果:黄芩、黄连、黄柏、甘草、知母、桅子、赤芍可在不同的薄层条件下分别检出;利用高效液相色谱法测定制剂中黄芩的有效成分黄芩苷,黄芩苷在0.20~1.60μg范围内线性关系良好(r=0.999 8),平均回收率为98.46%,RSD为2.89%(n=6)。结论:该法专属性强,重复性好,可用于清胃黄连片的质量控制。 相似文献
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目的:观察中医药治疗轻中度艾滋病痴呆综合征的疗效。方法:30例艾滋病痴呆综合征患者随机平均分为治疗组和对照组。治疗组根据中医辨证给予中药治疗,对照组口服银杏叶片治疗,观察两组简易智能评分量表(MMSE)评分、日常生活活动能力(ADL)评分的改善情况。结果:治疗后MMSE评分治疗组为(25.36±5.13)分,对照组为(11.47±5.01)分,两组比较,差异有显著统计学意义(P〈0.01);ADL评分治疗组为(51.63±13.31)分,对照组为(34.20±11.43)分,两组比较,差异有显著统计学意义(P〈0.01)。结论:中医药治疗轻中度艾滋病痴呆综合征疗效较好。 相似文献
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M. E. L. MOON BS MB I. F. ROBERTSON FRACO FRACS 《Clinical & experimental ophthalmology》1983,11(4):281-286
This report examines the epidemiology, management and morbidity of 159 cases of alkali burns of the eye admitted to The Royal Victorian Eye and Ear Hospital from 1972 to 1981. It was intended to use this as a basis for future accurate assessment and management of this problem. Grading of burns on information provided within the histories was according to Hughes' classification as modified by Ballen. Aspects examined were type of alkali, nature of accident, treatment, complications and follow-up. Results showed that the majority of burns were grade 1 or 2; only a few grade 1 and slightly more grade 2 burn patients suffered any complications, and none of these resulted in loss of vision. All patients with grade 3 and 4 burns suffered severe complications. It would appear that grade 3 and 4 burns need a more specific and energetic plan of treatment. Lime was the most common agent, and the largest group involved comprised male workers who suffered injuries at work. On the basis of the findings of the study the following points are raised: (i) a protocol for future study is suggested; (ii) there is a need tor a more discriminate use of EDTA: (iii) do grade 1 burns require hospital admission?; (iv) treatment of grade 3 and 4 burns is still unsatisfactory; (v) the public must be made aware of the existing dangers of alkali burns and their prevention. 相似文献
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目的:探讨黄连解毒汤(HLJDD)对APP/PS1双转基因阿尔茨海默病(AD)模型小鼠海马CA1区的病理形态学及脑内β-淀粉样前体蛋白(β-APP)基因mRNA的影响。方法:选用3月龄的APP/PS1双转基因AD小鼠模型50只,随机分为对照组、安理申组、HLJDD大剂量组、HLJDD中剂量组、HLJDD小剂量组各10只,分别给予安理申或不同剂量HLJDD灌胃治疗6个月,对照组不予治疗,记录并比较各组死亡率;分别于6月龄和10月龄时采用HE染色观察各组海马CA1区神经细胞形态,采用改良甲醇刚果红染色观察各组老年斑形成情况;于末次灌胃治疗后,通过实时荧光定量PCR检测各组脑内β-APPmRNA水平。结果:各组小鼠死亡率差异无统计学意义;10月龄HLJDD各剂量组海马CA1区神经损伤情况较对照组明显减轻,老年斑数量少于对照组(P0.05);HLJDD各剂量组β-APPmRNA水平低于对照组(P0.05),其中以中剂量组水平降低最明显(P0.01)。结论:HLJDD能保护海马神经细胞。 相似文献
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萸连巴布剂体外释放和透皮行为的研究 总被引:11,自引:3,他引:8
目的:考察萸连巴布膏的体外释放和透皮行为和规律.方法:试验采用改良Franz扩散装置,用HPLC法使用1种流动相测定接收液中吴茱萸碱、吴茱萸次碱、巴马汀、小檗碱4种指标成分的含量.结果:吴茱萸碱、吴茱萸次碱、巴马汀、小檗碱释放速率分别为0.023 9,0.015 6,0.072 5,0.819 1 mg·cm~(-2)·h~(-1/2);透皮速率分别为1.256,1.030 2,2.802 9,20.919μg·cm~(-2)·h~(-1).结论:萸连巴布剂的体外释放符合Higuchi方程,透皮行为为零级过程. 相似文献
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